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MCRN

An Introduction to Variational Data Assimilation

Naratip Santitissadeekorn gives an introductory survey of variational techniques in data assimilation including 3D-VAR and 4D-VAR. This talk was given on 10-2-14. Naratip Santitissadeekorn gives an introductory survey of variational techniques in data assimilation including 3D-VAR and 4D-VAR. This t…
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MCRN

Statistical Data Assimilation For Parameter Estimation In Costal Ocean Hydrodynamics Modeling

Coastal ocean models are used for a variety of applications, including modeling tides and hurricane storm surge. These models numerically solve the shallow water equations, which are derived by depth integrating the Navier-Stokes equations. The inherent uncertainties in coastal ocean models are a re…
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MCRN

Complex Energy Systems

This is the opening guest lecture for the Electric Grid Focus Group. Dr. Michael Chertkov of Los Alamos National Lab describes the statistical and mathematical problems arising in complex energy systems, including the electric grid and gas networks. Systems with high penetration of renewable energy …
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Nano/Bio Connection

Nanotechnology is not just a topic for physicists, chemists, and engineers. Laura explains the important role of biologists in this field, and shows how they may help provide clues to molecular assembly techniques. Nanotechnology is not just a topic for physicists, chemists, and engineers. Laura exp…
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Illinois BioNanotechnology Seminar Series Fall 2011: Magnetomotive Molecular Nanoprobe

Magnetomotive Molecular NanoprobeThe diagnostic, interrogational, and therapeutic potential of molecular nanoprobes is rapidly being investigated and exploited across virtually every biomedical imaging modality. While many types of probes enhance contrast or delivery therapy by static localization t…
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Illinois BioNanotechnology Seminar Series Fall 2011: Multi-Modal and Multi-Functional Magnetic Particles for Cancer Imaging

Differential adhesion between cadherin subtypes expressed on cell surfaces is postulated to direct cell segregation during tissue morphogenesis. The studies described here used magnetic twisting cytometry and traction force microscopy to test the impact of cadherin binding selectivity on mechanotran…
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Illinois BioNanotechnology Seminar Series Fall 2011: Mechanotransduction at Cell-Cell Contact

Differential adhesion between cadherin subtypes expressed on cell surfaces is postulated to direct cell segregation during tissue morphogenesis. The studies described here used magnetic twisting cytometry and traction force microscopy to test the impact of cadherin binding selectivity on mechanotran…
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Illinois BioNanotechnology Seminar Series Fall 2011: Investigating Dendritic Filopodial Dynamics in Highly Controlled Microenvironments

The establishment of the intricate wiring of the nervous system relies on filopodial navigation to form complex interconnections between neurons. Until recently, cellular level investigations into filopodial dynamics had focused primarily on axonal growth cone filopodia. Here we focus on their oft i…
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MCRN

Extending the square root method to account for model noise in the ensemble Kalman filter

Presented by Patrick Raanes on 2-18-2015 Abstract:A novel approach to account for model noise in the forecast step of the Ensemble Kalman filter (EnKF) is proposed. The core method is based on the approach of the analysis step of ensemble square root filters (ETKF), and consists in right-multiplying…
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MCRN

Andy Reagan: Masters Thesis

Andy Reagan at UVM gives a talk about his masters work on uncertainty quantification and data assimilation to improve the numerical prediction of fluids in the thermosyphon. This talk will involve several data assimilation methods, including variational techniques, but will focus on LETKF. This talk…
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MCRN

Correlated Observation Errors in Data Assimilation

Remote sensing observations often have correlated errors, but the correlations are typically ignored in data assimilation for numerical weather prediction. The assumption of zero correlations is often used with data thinning methods, resulting in a loss of information, and reduction in analysis accu…
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MCRN

Toward a hybrid particle-ensemble Kalman filter for assimilating data from Lagrangian instruments into high dimensional models

Presented by Elaine Spiller on 3-26-15Abstract:We discuss a recently proposed hybrid particle-ensemble Kalman filter for assimilating Lagrangian data, and apply it to a high-dimensional quasi-geostrophic ocean model. Effectively the hybrid filter applies a particle filter to the highly nonlinear, lo…
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MCRN

Particle filters for geophysical applications

Avoiding degeneracy is a crucial challenge for particle filters. Results have shown that the number of particles scales exponentially with respect to the number of independent observations. In this talk I will review attempts to counteract this phenomenon by exploiting proposal densities. I will put…
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MCRN

Realistic modeling and analysis of synchronization dynamics in power-grid networks

An imperative condition for the functioning of a power-grid network is that its power generators remain synchronized. Disturbances can prompt desynchronization, which is a process that has been involved in large power outages. In this talk I will first give a comparative review of three leading mode…
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Introduction to Molecular Conduction

A scanning probe microscope brushes the tips of molecules rising up from a gold substrate. After making contact, the probe measures a very strange current-voltage relationship--linear portions separated by flat spots or sharp increases. Definitely not Ohm's law. Is the experiment correct? What d…
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Illinois BioNanotechnology Seminar Series Fall 2011: In vitro Cancer Metastasis Driven by Elasticity of Micro-environment

Cancer deaths are primarily caused by metastases, not by the parent tumor. However, the physical-chemical mechanisms and parameters within the cellular micro-environment that initiate the onset of metastasis, are not understood. Here we show that human colon carcinoma (HCT-8) cells can exhibit a dis…
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[Illinois] BioNanotechnology Seminar Series Fall 2011: Bio-inspired Microenvironments Regulate Cell Fate

Epigenetic regulation of stem cell fate by intrinsic properties of the surrounding extracellular matrix (ECM), e.g. stiffness, organization, composition, etc., appears to be an important yet underappreciated contributor in development, disease, and aging. I will describe our efforts to develop biomi…
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Illinois BioNanotechnology Seminar Series Fall 2011: Precisely Size Controlled Drug-silica Nanoconjugate for Cancer Therapy

Drug delivery nanomedicine, exemplified by micelles and nanoparticles roughly in the size range of 1-200 nm, have attracted much interest in the past 2-3 decades as alternative modalities for cancer treatment. The size of these drug delivery vehicles has been strongly correlated with their in vivo b…
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Illinois BioNanotechnology Seminar Series Fall 2011: Deconvolving Stiffness in MEMS Pedestal Cell Mass Measurements

The complex relationships between a cell's behavior and the physical properties of both itself and its environment have long been of interest. Specifically, the understanding the mechanisms through which a cell's physical properties influence cell growth, cell differentiation, cell cycle progression…
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