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Rotating Drum

Rotating drums have been studied in the pharmaceutical industry for a long time. Flows in rotating drums are divided into distinct regimes:Rolling regime: Powder on the surface cascades down the incline and powder at the bottom rotates with the drum.Slumping regime: Back and forth rocking motion of … Launch Tool
  • Resource Tools
Pharmahub

High Shear Mixer

Granular mixing remains an art rather than a science and is a hot research topic in adademia as well as in industry. Granular materials display wide range of behaviour ranging from poor mixing to segregation based on mixer characteristics and operating regimes. Understanding how the materials in the… Launch Tool
  • Resource Tools
Pharmahub

Discrete Element Method (DEM) Course Module

The DEM course module was created by Carl Wassgren of the Particulate Systems Laboratory (PSL) at Purdue University. The series consists of slides and videos that will familiarize you with the basics of DEM. Discrete Element Method has been applied to analyze and predict flow behaviour in a wide var…
  • Resource Courses
Pharmahub

Visualization of Particle-Based Computer Data

The ParticleVis software system offers full-featured visualization of discrete element method (DEM) computer data for real-time 3D rendering of large sets of particle states. ParticleVis capabilities include:adjustable lighting conditions and camera viewing characteristics,options to display transla…
  • Resource Series
Pharmahub

PSL DEM Lecture 03: Hard Particle Contact Detection

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 03: Hard Particle Contact Detection. The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. Thi…
  • Resource Teaching Materials
Pharmahub

PSL DEM Lecture 02: Hard Particle Collision Modeling

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 02: Hard Particle Collision Modeling The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. Thi…
  • Resource Teaching Materials
MCRN

Extending the square root method to account for model noise in the ensemble Kalman filter

Presented by Patrick Raanes on 2-18-2015 Abstract:A novel approach to account for model noise in the forecast step of the Ensemble Kalman filter (EnKF) is proposed. The core method is based on the approach of the analysis step of ensemble square root filters (ETKF), and consists in right-multiplying…
  • Resource Presentations
Pharmahub

ParticleVis: A Tool for DEM Particle Visualization

ParticleVis is a visualization tool specialized for loading and exploring particulate simulation data. It contains a set of features that enables powerful and useful visualizations of particle simulations to be quickly generated. Support is provided for visualization of hundreds of thousands of part…
  • Resource Downloads
Pharmahub

Video Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I

Video Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I Video Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part ICarl R. WassgrenParticulate Systems Laboratory (PSL), Purdue University …
  • Resource Animations
Pharmahub

PSL DEM Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 06: Introduction to Soft-Particle DEM and Normal Contact Force Models - Part I. The Particulate Systems Laboratory at Purdue University presents the Discrete Elem…
  • Resource Teaching Materials
Pharmahub

PSL DEM Lecture 01: Motivation

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 01: Motivation. The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 01: Moti…
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Pharmahub

Inter- and Intra- Tablet Coating Variability

Tablets are coated for a number of reasons, the most important of which is controlling the release profiles and bioavailability of the active pharmaceutical ingredient. The amount of coating on the surface of a tablet is critical to the effectiveness of the oral dosage form.Tablets are usually coate…
  • Resource Animations
Pharmahub

PSL DEM Lecture 11: Coarse Contact Detection

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 11: Coarse Contact Detection. The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Le…
  • Resource Teaching Materials
Pharmahub

Hopper Flow

Hoppers are commonly used devices for handling and storing granular materials. Despite their common use and deceptivelysimple design, hoppers have a number of problems associated with them, including funnel flows, choking, bridging, and flooding.Some funnel flows are characterized by stagnant region… Launch Tool
  • Resource Tools
Pharmahub

PSL DEM Lecture 07: Normal Contact Force Models - Part II

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 07: Normal Contact Force Models - Part II. The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Serie…
  • Resource Teaching Materials
Pharmahub

PSL DEM Lecture 13: 3D Rotations

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 13: 3D Rotations. The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 13: 3D…
  • Resource Teaching Materials
Pharmahub

Hopper Segregation

The Particulate Sciences Laboratory at Purdue University investigates the mixing and segregation of binary and multi-component granular materials. Solids mixing, also known as blending, is a common processing operation used in the manufacture of pharmaceutical products. The intent of mixing operatio…
  • Resource Animations
Pharmahub

PSL DEM Lecture 09: Tangential Contact Force Models

The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This is Lecture 9: Tangential Contact Force Models. The Particulate Systems Laboratory at Purdue University presents the Discrete Element Modeling (DEM) Short Course Series. This…
  • Resource Teaching Materials

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